Search on: CORTICOTROPIN-RELEASING HORMONE 
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Descriptor English:   Corticotropin-Releasing Hormone 
Descriptor Spanish:   Hormona Liberadora de Corticotropina 
Descriptor Portuguese:   Hormônio Liberador da Corticotropina 
Synonyms English:   ACTH-Releasing Hormone
Corticotropin-Releasing Factor
Corticotropin-Releasing Hormone-41
CRF-41  
Tree Number:   D06.472.699.327.740.140
D12.644.400.400.740.140
D12.644.548.365.740.140
D12.776.641.650.405.740.140
Definition English:   A peptide of about 41 amino acids that stimulates the release of ADRENOCORTICOTROPIC HORMONE. CRH is synthesized by neurons in the PARAVENTRICULAR NUCLEUS of the HYPOTHALAMUS. After being released into the pituitary portal circulation, CRH stimulates the release of ACTH from the PITUITARY GLAND. CRH can also be synthesized in other tissues, such as PLACENTA; ADRENAL MEDULLA; and TESTIS. 
Indexing Annotation English:   DF: CRH
Pharmacological Action:   Hormones
 
See Related English:   Receptors, Corticotropin-Releasing Hormone
 
History Note English:   90; was CORTICOTROPIN RELEASING HORMONE 1974-89; was CORTICOTROPIN RELEASING FACTOR 1968-73 
Allowable Qualifiers English:  
analogs & derivatives administration & dosage
adverse effects agonists
antagonists & inhibitors analysis
biosynthesis blood
cerebrospinal fluid chemistry
classification chemical synthesis
contraindications drug effects
deficiency diagnostic use
economics genetics
history immunology
isolation & purification metabolism
pharmacology physiology
pharmacokinetics poisoning
radiation effects supply & distribution
secretion standards
toxicity therapeutic use
urine  
Record Number:   22405 
Unique Identifier:   D003346 

Occurrence in VHL: 		 

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